This live session, taped at SXSW 2025, explores the interplay between higher education and artificial intelligence, delving into how academic institutions are responding to the proliferation of AI in the workplace and economy. Leaders from academia, economic development, and industry discuss how universities and colleges are advancing research and equipping students with the skills to lead in an AI-powered future. From addressing social inequities to preparing cities for the economy of the future, the conversation highlights the transformative potential of AI when nurtured within higher education, and the tradeoffs that must be made in an education system wired for the past.